• The Department of Emergency Medicine is nationally recognized for its innovative clinical and translational research, ranking 18th in National Institutes of Health (NIH) funding for academic emergency departments.

Research

Highlighted Clinical Trials

RED CORAL: PETAL Repository of Electronic Data COVID-19 Observational Study

Status: Active
Period: March 2020 to June 2020
NCT ID: N/A

Rational
The epidemiology of patients hospitalized with severe COVID-19 has not been well defined, especially in the American context. There are significant knowledge gaps regarding demographics, clinical characteristics, trajectory of disease, timing of recovery, predictors of organ failure and death, resource utilization, and post-hospital outcomes. In response, the purpose of the RED CORAL study is to inform epidemiology and resource utilization through data collection and creation of a data repository.

The Prevention and Early Treatment of Acute Lung Injury (PETAL) Network is a consortium of academic and affiliated hospitals across the United States, funded by the NHLBI to conduct clinical trials in patients with or at risk for critical illness, including ARDS. Our Network’s goal is to improve outcomes of patients with acute and critical illness through research.

Study Aim
We will identify acute and critically ill patients with COVID-19 and collect detailed data from their hospital stay. We will contribute data to the WHO/ ISARIC COVID registry and to the scientific community in order to advance United States participation in studies of global epidemiology. We will use the data to increase understanding of the clinical course of COVID-19.

Study Population
RED CORAL will include adult patients with confirmed COVID-19 hospitalized at participating sites who have available clinical data. The study period will include patients who present for admission to study hospitals between March 1 and April 1, 2020.

 

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Research News

Dr. Srikar Adhikari Receives EMF Grant to Study Artificial Intelligence for Prognosis of Ultrasound of the Lung in COVID

Srikar Adhikari, MD, professor of emergency medicine and director of the Emergency Medicine Ultrasound Fellowship, received an Emergency Medicine Foundation (EMF) and FUJIFILM Sonosite’s grant, which included a new Sonosite PX point-of-care ultrasound system, to support his research, "Artificial Intelligence for Prognosis of Ultrasound of the Lung in COVID (AI PULL),” examining the role of point-of-care ultrasound in the clinical care of COVID-19 patients.


Implementing Pediatric Prehospital Care Guidelines Dramatically Improves Survival in Severe Traumatic Brain Injury

Emergency medicine guidelines to ensure continued flow of blood and oxygen to the brain are emphasized in study that undescores the first 26 minutes of care on the scene of an accident or fall are critical to survival and ongoing brain health.


Lung Ultrasound Training to Help Rural Emergency Medicine Providers Diagnose COVID-19 Patients

The tele-ultrasound training program for lung point-of-care ultrasound (POCUS) will enable rural emergency departments to more effectively identify and treat suspected COVID-19 patients.


Selected Recent Publications

Dalen JE, Stein PD, Plitt JL, Jaswal N, Alpert JS. "Extended Thromboprophylaxis for Medical Patients." Am J Med. 2020;133(1):9-11.
Hughes KE, Hughes PG, Cahir T, et al. "Advanced closed-loop communication training: the blindfolded resuscitation." BMJ Simulation and Technology Enhanced Learning. 2020;6(4):235-238.
Rinner GR, Watkins SA, Shirazi FMazda, et al. "Fatal abrin poisoning by injection." Clin Toxicol (Phila). 2020:1-3.
Dalen JE, Plitt JL, Jaswal N, Alpert JS. "An Alternative to Medicare for All." Am J Med. 2019;132(6):665-667.
Acuña J, Situ-LaCasse EH, Patanwala AE, et al. "Identification of gender differences in ultrasound milestone assessments during emergency medicine residency training: a pilot study." Adv Med Educ Pract. 2019;10:141-145.