| Title | Oxyhemoglobin saturation measurements by green spectral shift. |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Denninghoff KR, Chipman RA, Hillman LW |
| Journal | Opt Lett |
| Volume | 31 |
| Issue | 7 |
| Pagination | 924-6 |
| Date Published | 2006 Apr 1 |
| ISSN Number | 0146-9592 |
| Keywords | Algorithms, Blood Chemical Analysis, Computer Simulation, Humans, Models, Chemical, Oximetry, Oxyhemoglobins, Spectrum Analysis |
| Abstract | From an analysis of new hemoglobin solution transmission spectra at various oxygen saturations (SO2), path lengths, and pH, we find the determination of SO2 by using the classical oximetry technique to be poorly calibrated. We used this data set to develop a proposed method for SO2 determination based on the spectral shift of the hemoglobin transmission minimum between 475 and 510 nm. The method does not require accurate knowledge of hemoglobin extinction coefficients and is linear in relation to SO2 despite changes in path length, pH, or hemoglobin concentration. |
| Alternate Journal | Opt Lett |
| PubMed ID | 16599213 |
Faculty Reference:
Kurt Denninghoff, MD