Effect of multiple light paths on retinal vessel oximetry.

TitleEffect of multiple light paths on retinal vessel oximetry.
Publication TypeJournal Article
Year of Publication2000
AuthorsSmith MH, Denninghoff KR, Lompado A, Hillman LW
JournalAppl Opt
Volume39
Issue7
Pagination1183-93
Date Published2000 Mar 1
ISSN Number0003-6935
Abstract

Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.

Alternate JournalAppl Opt
PubMed ID18338002
Faculty Reference: 
Kurt Denninghoff, MD